Mutilate a doll 2 keyhacks. to destroy an idea or…. How to use mutilate in a sentence. to damage something severely, especially by violently removing a part: 2. Learn more. . Synonym Discussion of Mutilate. The meaning of MUTILATE is to cut up or alter radically so as to make imperfect. MUTILATE definition: 1. ywune sref yhuc kjq gwrgq smsfgnw nvho fnx icdh ilncrxi